Episode #43: Acetaminophen

In this episode, Victoria and guest host Amanda Jones are joined again by Bob Block, PharmD (be sure to watch our episode with him on ivermectin).

We asked Bob to come back just a few days after publishing our ivermectin episode to offer a more complete baseline of information on acetaminophen, also known as paracetamol.

In this episode, they discuss:

* Acetaminophen, N-acetyl-para-aminophenol (APAP) or paracetamol in many countries, a non-opioid analgesic and antipyretic agent utilized for treating pain and fever

* Acetaminophen’s mechanism of action, aka how it works to relieve pain and fever

* The recent press conference that put acetaminophen in the spotlight

* FDA news release: Evidence of Possible Association Between Autism and Acetaminophen Use During Pregnancy

* Research on this topic, including:

* Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology

* Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability

* Click here for an excellent interview with this study’s author

* The relationship of prenatal acetaminophen exposure and attention-related behavior in early childhood

* Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis

* Maternal fever during pregnancy and offspring attention deficit hyperactivity disorder

* Maternal inflammation may increase the risk of NDDs independent of treatment

* Effects of maternal psychological stress during pregnancy on offspring brain development: Considering the role of inflammation and potential for preventive intervention

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