From Our Neurons to Yours How basic science transformed stroke care | Marion Buckwalter
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Jun 26, 2025 
In this captivating discussion, Marion Buckwalter, a physician scientist at Stanford specializing in neurocritical care, shares her insights on the remarkable evolution of stroke treatment. She reveals how recent advancements, from AI-enabled imaging to innovative thrombolytic therapies, have drastically changed patient outcomes. Buckwalter stresses the importance of ongoing investment in basic science research to prevent stagnation in breakthroughs and highlights the exciting future that could await us if we maintain our focus on these foundational studies.
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Impact of Large Brain Artery Strokes
- Large clots in major brain arteries cause severe strokes with paralysis and language deficits.
- The left middle cerebral artery stroke particularly affects language and motor functions on the right side.
Revolution in Real-Time Stroke Treatment
- Modern stroke care uses imaging and clot-busting drugs to quickly restore blood flow.
- Catheter-based clot removal can prevent extensive brain damage if done promptly.
Clinician's Experience with Stroke Care
- Treating large strokes with clot removal is transformative for clinicians and families.
- Seeing patients regain speech and movement quickly after intervention is exhilarating.