3 Takeaways

Dr. David Agus on The Hopeful Science of a Longer, Healthier Life (#280)

Dec 16, 2025
Dr. David Agus, a renowned physician and author, dives into the science of longevity and prevention. He reveals that a mere 4% of our lifespan is genetic—96% is within our control! Discover how elephants avoid cancer and the importance of habits like regular movement and good nutrition. Agus emphasizes the critical role of inflammation and innovative AI methods in healthcare. He shares practical advice to enhance health, highlighting that optimism and personal responsibility can lead to a longer, healthier life.
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INSIGHT

Longevity Is Largely Under Your Control

  • Only about 4% of longevity is genetic, so most lifespan is shaped by behavior.
  • Dr. David Agus says this makes health outcomes largely within our control.
ADVICE

Prevent Early, Use Data To Predict

  • Shift resources and interventions earlier in life to prevent disease and improve outcomes.
  • Use AI and data to predict outcomes and intervene before late-stage costly care.
ANECDOTE

Rejuvenation From Shared Blood Circulation

  • Wanda Rust Lunsford tied old and young rats together and saw the old rat rejuvenate.
  • Modern labs replicated the experiment and found circulating factors can reactivate stem cells.
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