The Curbsiders Internal Medicine Podcast #319 Hotcakes: Afib, Chlorthalidone in CKD, Outpatient COVID Treatment Update
Jan 31, 2022
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Yaktrax Saved Runs On Ice
- Rahul shared a personal pick: yaktrax cleats transformed his winter runs and prevented slips on ice.
- He recommended them strongly after using them on icy runs.
Patient-Led N-of-1 Trials In Afib
- N-of-1 trials let patients test their own triggers for paroxysmal atrial fibrillation.
- The I-STOP Afib trial found no average improvement in AF-related quality of life despite some trigger-related effects.
When To Use N-of-1 Designs
- Use n-of-1 designs for stable conditions with clear symptoms or biomarkers and quick on/off treatment effects.
- Avoid them for catastrophic or slowly progressive outcomes like MI or death.