
 Off Limits w/ Bryan Callen
 Off Limits w/ Bryan Callen THE GREATEST THREAT TO HUMANITY | Limits Bret Weinstein
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 Jul 18, 2025  Bret Weinstein, an evolutionary biologist and host of The DarkHorse Podcast, dives into the challenges of our modern discourse. He critiques public trust in science and explores the complexities around vaccine skepticism and health distrust. The conversation also tackles the ethical implications of medical interventions on children and the paradox of technological progress on health. With sharp insights into the pharmaceutical industry's motives, Bret emphasizes the need for transparency and critical thinking in navigating health choices. 
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True Expertise Requires Humility
- True experts move toward being more correct as new information arises.
- Radical humility about what we know is essential in understanding complex biological systems.
Polarization Obscures Truth
- Society is polarized, forcing people into opposing camps without space for nuance.
- This polarization creates distrust and confusion on where to find truth especially around topics like vaccines.
Bret's Journey on Vaccine Views
- Bret initially respected RFK Jr. for his environmentalism but was troubled by his anti-vaccine stance.
- Over time Bret found parts of RFK Jr.'s controversial claims had evidentiary support, challenging common narratives.




