

343: Turbulence at the FDA, Bluebird Bio's sale and young biotech VCs
16 snips Feb 27, 2025
Lizzy Lawrence, a STAT reporter, gives us an inside look at the current turmoil at the FDA, detailing the chaos of frequent staffing changes and its impact on morale. Jason Mast then discusses the acquisition of Bluebird Bio, shedding light on the company's challenges in gene therapy and its drastic fall from grace. The conversation also touches on the rise of new biotech VCs, fueled by technological advancements and the pandemic, setting the stage for a dynamic shift in the industry.
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Rise of Biotech VC
- Biotech VC investments remained steady until 2017, then increased dramatically.
- This surge fueled new VC firms with younger founders from diverse backgrounds.
FDA Turmoil
- FDA employees face firings and rehirings with little explanation, impacting morale.
- Lizzie Lawrence's reporting relies on insider sources due to lack of official communication.
Makari's Hearing
- Upcoming confirmation hearing for Trump's FDA nominee, Marty Makari, is anticipated.
- Makari's approach to FDA disarray and food regulation overhaul will be scrutinized.