JAMAevidence JAMA Guide to Statistics and Methods cover image

JAMAevidence JAMA Guide to Statistics and Methods

Odds Ratios—Current Best Practice and Use With Dr Norton

Nov 2, 2023
Dr. Edward C. Norton discusses the best practices and applications of odds ratios in different fields, from gambling to medical research. They also explore the impact of controlling for factors in regression and demonstrate how odds ratios can be altered by various models. Additionally, they discuss the significance of controlling for specialty when examining the effect of gender on industry payments.
12:19

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Quick takeaways

  • Odds ratios are commonly used to measure the effects of treatments or risk factors on the probability of a patient experiencing a specific outcome.
  • Adding clinical risk factors in logistic regression models can alter the magnitude of association and necessitate alternative measures for effective interpretation.

Deep dives

Understanding Odds and Odds Ratios

Odds are a ratio of the chance of something happening divided by the chance of it not happening. They are useful for gamblers to determine fair bets. Odds ratios are commonly used to measure the effects of treatments or risk factors on the probability of a patient experiencing a specific outcome. The odds ratio compares the odds of the outcome for one group to the odds of the outcome for another. An odds ratio of 1 indicates that the outcome is equally likely for both groups, while an odds ratio below 1 suggests a lower likelihood of the outcome in the treated group.

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