Anne McElvoy, Senior Editor at The Economist, and Natasha Loader, Health Policy Editor, delve into the latest UK cabinet reshuffle, analyzing its implications for Boris Johnson's leadership and agenda amidst public scrutiny. They also tackle a groundbreaking coronavirus human challenge trial, discussing the ethical dilemmas and insights gained from deliberately infecting volunteers. Additionally, they highlight rural opportunities in places like Creed, Colorado, aiming to attract tourists by promoting their pristine dark skies.