

#84 Dr Brianna Cardenas & Dr. Andrew Maxwell discuss Cerebrospinal Fluid (CSF) leaks
7 snips Apr 7, 2025
Dr. Brianna Cardenas, a Physician Assistant specializing in chronic illness and founder of Healed and Empowered, shares her insights on cerebrospinal fluid (CSF) leaks, informed by her experience with Ehlers-Danlos Syndrome. She and Dr. Andrew Maxwell, a Pediatric Cardiologist with expertise in environmental health, dive into the anatomy of CSF leaks, their symptoms, and why they often go undiagnosed. They discuss innovative treatments like blood patches and the role of fascial therapy, emphasizing the importance of patient advocacy in navigating complex health challenges.
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Dr. Cardenas' CSF Leak Journey
- Dr. Brianna Cardenas experienced worsening symptoms including nausea, brain fog, and collapsing due to multiple cerebrospinal fluid (CSF) leaks.
- Despite many negative tests, she self-educated and found she had six leak sites, undergoing 21 spine procedures to regain function.
CSF and Meninges Essential Roles
- CSF bathes our brain and spinal cord, protected by meninges: pia, arachnoid, and dura mater.
- In connective tissue disorders like EDS, dura is thinner and weaker, causing potential leaks and symptoms affecting any nerve in the body.
Leaky Brain and Pressure Dysregulation
- Chronic inflammatory or environmental stress can damage dura mater, causing leaky brain similar to leaky gut.
- Overpressurization obstructs CSF drainage leading to diverse, fluctuating symptoms by affecting nervous system signaling.