Some of the input data is missing for some studies. How do you deal with these missings - just exclude them?
You compare many treatments with each other in a pairwise way. How do you best communicate this large matrix of pairwise comparisons?
You need to adapt your NMA last minute because there was a delay in the system and your systematic literature search became outdated. Do you need to postpone the launch of the new product by a couple of weeks?
You got regulatory approval for a new indication earlier than expected. While the regulatory team celebrates the achievement you worry that you need to have your NMA ready 3 months earlier. Will you be able to deliver?
We discuss these and many more problems of NMAs.
If you would like to get help around these, write an email to alexander@theeffectivestatistician.com or contact me via LinkedIn.
The Effective Statistician - in association with PSI