

Estrogen Exposure from Modern Hormonal Contraceptives and Vascular Risk in Women with Migraine: A Nationwide Electronic Health Record Database Study
Apr 16, 2025
Discover the intriguing relationship between hormonal contraceptives and vascular risks in women who suffer from migraines. A recent study shows no major differences in vascular health between users and non-users of estrogen-containing contraceptives. However, it sheds light on an increased stroke risk for non-user women experiencing migraine with aura. Tune in to unpack these findings and their implications for women's health!
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Low-Dose Estrogen Contraceptives Safe
- Combined hormonal contraceptives with low-dose estrogen do not increase vascular risk in women with migraine.
- Migraine with aura raises vascular risk only among women not using these contraceptives.
Aura Increases Stroke Risk
- Women with migraine with aura have a higher incidence of ischemic stroke when not using hormonal contraceptives.
- This risk difference is less clear among users of combined hormonal contraceptives.
Follow Headache Society Guidelines
- Clinicians can safely follow International Headache Society guidelines to prescribe combined hormonal contraceptives in women with migraine.
- This applies to women both with and without aura, reflecting current clinical practice evidence.