BackTable Vascular & Interventional

Ep. 604 Mythbusters: Provocative Mesenteric Angiography for GI Bleeds with Dr. Sabeen Dhand

11 snips
Jan 6, 2026
Dr. Sabeen Dhand, an interventional radiologist and procedural expert, dives into the world of provocative mesenteric angiography for GI bleeds. She uncovers the protocols for administering tPA, emphasizing careful dosing and communication with care teams. Addressing common myths, Dr. Dhand explains when to utilize provocative angiography after negative tests. With fascinating real-world case studies, she showcases the procedure's safety and efficiency, challenging misconceptions and highlighting its critical role in managing recurrent lower GI bleeding.
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ADVICE

When To Use Provocative Angiography

  • Do plan provocative mesenteric angiography for recurrent lower GI bleeds after negative CTA and negative initial angiogram.
  • Do involve multidisciplinary teams and prepare for controlled settings like GA when you intend to provoke bleeding.
ADVICE

Optimize SMA Runs And Prep Medically

  • Do use a sheath for SMA runs and flood the territory with contrast to maximize detection.
  • Do give 10,000–15,000 units heparin IV and nitroglycerin (200–500 mcg) before starting tPA injections to help elicit bleeding.
ADVICE

tPA Dosing Strategy

  • Do use incremental intra-arterial tPA boluses (2 mg vials diluted to 1 mg/cc) given slowly while repeating angiographic runs.
  • Do cap total tPA around 50 mg combined between territories and wait between boluses to look for subtle blushes.
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