The Curbsiders Internal Medicine Podcast

#476 Medications for Alcohol Use Disorder 2.0 with Dr Stephen Holt

53 snips
Mar 24, 2025
Dr. Stephen Holt, an Associate Professor at Yale, shares his expertise in addiction medicine. He delves into innovative treatments for alcohol use disorder, discussing lesser-known medications like disulfiram and topiramate. The importance of personalized care shines through, advocating for individual treatment goals that may include moderation. He explores the effectiveness of targeted naltrexone and emphasizes the role of compassionate relationships in recovery. Listeners gain insights into medication adherence and the significance of clear communication between doctors and patients.
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ADVICE

Alternative Medication Strategies

  • Consider alternate naltrexone/acamprosate strategies if first-line options fail.
  • Try 100mg naltrexone or discuss targeted naltrexone use.
INSIGHT

Redefining Success in AUD Treatment

  • Success in AUD treatment isn't solely abstinence; harm reduction matters.
  • Prioritize patient-centered goals like reduced consumption or safer drinking habits.
INSIGHT

Beyond Abstinence-Only

  • The "abstinence-only" view can be harmful.
  • Embrace mutual support groups promoting medication and moderation.
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