Blood Biomarkers for Alzheimer's Diagnosis

A study evaluated the effectiveness of blood biomarkers for diagnosing Alzheimer's disease in both primary and secondary care settings. Conducted in Sweden, this research involved patients already suspected of cognitive impairment and assessed them using blood biomarkers alongside lumbar punctures and PET scans for confirmation. The findings showed that blood tests, particularly the phosphorylated tau ratio and an amyloid protein score, provided a significant diagnostic accuracy, outperforming clinical assessments from specialists and primary care. Although promising, the study acknowledged limitations, including its small size and lack of generalizability beyond the Swedish population.