Core IM | Internal Medicine Podcast
#175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group
Apr 16, 2025
The discussion delves into the evolution of HIV prevention strategies, comparing oral PrEP options like Truvada to innovative long-acting injectables. The groundbreaking PURPOSE trials showcase lenacapavir's impressive efficacy, particularly in diverse populations, revealing zero infections among treated cisgender women. Barriers to access and adherence are critically examined, emphasizing the need for equitable solutions. With promising results on the horizon, the future of HIV prevention looks brighter, potentially revolutionizing care for those at risk.
27:44
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Quick takeaways
- The Purpose trials highlight the potential of lenacapivir as a revolutionary HIV prevention method while addressing adherence challenges across diverse demographics.
- Understanding the difference between efficacy and effectiveness is crucial, as real-world adherence remains a significant barrier to successful HIV prevention.
Deep dives
Experiences in Editorial Fellowship
The editorial fellowship at the New England Journal of Medicine provides an immersive experience in the field of medical journalism and editorial processes. Participants engage in editorial meetings to discuss the suitability of various papers for publication, which enhances their understanding of scientific literature and research integrity. The fellowship also fosters leadership skills by teaching how to navigate scientific debates and facilitate conversations effectively. Additionally, the supportive culture among editors and staff offers informal learning opportunities that enrich the overall fellowship experience.
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