Core IM | Internal Medicine Podcast
#176 Constipation Medications: 5 Pearls Segment
Apr 30, 2025
Discover the high-yield reversible causes of constipation and which type of fiber is truly beneficial. Dive into the debate on hydration and the effectiveness of bulk-forming laxatives versus osmotic and stimulant options. Learn about the intricacies of suppositories and enemas as treatment methods. Get insights on managing opioid-induced constipation with innovative alternatives like peripheral opioid receptor antagonists. This enlightening discussion equips you with practical recommendations for optimizing patient care!
39:43
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Quick takeaways
- Understanding the mnemonic LMNOP is crucial for identifying reversible causes of constipation, which can significantly influence treatment strategies.
- Gradually increasing soluble fiber intake is effective in managing constipation, but must be balanced with hydration and medication timing considerations.
Deep dives
Understanding Constipation and Its Causes
Constipation can be defined as having fewer than three bowel movements a week, although individual norms vary. A mnemonic called LMNOP categorizes the reversible causes: Lifestyle factors such as lack of movement or low fiber intake, Metabolic issues like elevated calcium or low potassium affecting gut function, Neurologic disorders that impair bowel motility, Obstructions that may hinder stool passage, and Pharmacologic agents, including certain medications like tricyclic antidepressants and antipsychotics, which commonly induce constipation. Identifying the right category is essential as it can modify treatment approaches, emphasizing an investigative stance for practitioners to rule out secondary causes efficiently.
