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Business Trip

Holy poop! Mental health and the gut (part 1 with Holobiome)

Sep 14, 2023
Dr. Phil Strandwitz, Founder of Holobiome, discusses the gut-brain connection and pioneering microbial therapies. Trillions of gut bacteria influence neurotransmitter activity, mood, and cognition. Imbalances in the microbiome may underlie mental health issues. Startups like Holobiome aim to develop microbiome-based treatments including fecal transplants. Lifestyle changes like diet, prebiotics, and probiotics can support gut health. This conversation will change how you think about the gut-brain connection.
48:48

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Podcast summary created with Snipd AI

Quick takeaways

  • The gut microbiome has a significant impact on mental health and can influence neurotransmitters, mood, and cognition.
  • Targeting the gut microbiome with live bacteria as a therapeutic intervention shows promise for treating conditions like depression.

Deep dives

The Importance of the Gut Microbiome and its Influence on Mental Health

This podcast episode delves into the significance of the gut microbiome and its impact on mental health and wellness. The gut microbiome refers to the community of bacteria, viruses, archaea, and fungi that live in our bodies, particularly in the gut. These microorganisms have a crucial role in producing neurotransmitters and influencing bodily functions like mood and pain. The episode highlights the emergence of a new wave of entrepreneurs focused on developing therapeutics that target the gut microbiome to treat various conditions, including depression. Dr. Phil Stranowitz, the founder and CEO of Holobium, shares insights on the science of the gut microbiome, its interaction with the brain, and its potential applications in mental health. The discussion covers microbial therapeutics, the business aspect of this field, and various strategies to modulate the gut microbiome, including food, prebiotics, probiotics, and fecal transplants.

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