Cardionerds: A Cardiology Podcast 406. Journal Club: The BPROAD Trial with Dr. Keith Ferdinand
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Jan 15, 2025 Dr. Keith Ferdinand, a leading expert in hypertension at Tulane University, joins hosts to discuss the groundbreaking BPROAD trial. They explore the impact of intensive blood pressure management on cardiovascular outcomes in patients with type 2 diabetes. The conversation highlights the trade-offs of rigorous blood pressure targets and strategies for managing uncontrolled hypertension. Future directions in treatment, including cognitive health implications and advanced therapies like renal denervation, add to the intrigue, promising exciting developments in cardiovascular care.
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BP Goals in Diabetes
- Lowering blood pressure improves cardiovascular outcomes in type 2 diabetes patients, similar to the SPRINT trial.
- This confirms that tighter blood pressure control is beneficial, regardless of diabetes status.
Applying BP Road Findings
- Apply BP Road findings broadly, even to non-Chinese populations, due to the study's large sample size.
- Aggressively manage blood pressure in high-risk individuals, aiming for under 130 mmHg and potentially even lower.
Practical BP Management
- Increase medication doses like amlodipine and losartan for better control and consider a thiazide diuretic.
- Implement lifestyle changes, diabetes education, and home blood pressure monitoring for comprehensive management.