The Orthobullets Podcast Basic Science | Bone Grafting
Sep 8, 2025
Dive into the fascinating world of bone grafting! Discover the essential properties and types of grafts, including the pros and cons of autografts and allografts. Learn how vascularized grafts enhance healing and the challenges of disease transmission. The discussion also covers the critical characteristics of graft materials and their clinical applications. It's a treasure trove of information for anyone interested in orthopedic science!
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Three Core Graft Properties
- Bone graft materials work by osteoconduction, osteoinduction, or osteogenesis.
- Common examples include autograft, allograft, DBM, synthetics, BMP, and stem cells.
Scaffold Versus Signal
- Osteoconduction provides a scaffold while osteoinduction stimulates stem cells to form bone.
- Material 3D structure dictates how well it supports bone ingrowth.
Prefer Autograft For Cells
- Use autologous bone graft or bone marrow aspirate when you need live osteogenic cells.
- Autograft is the only graft source that reliably contains viable mesenchymal precursor cells.