The Curbsiders Internal Medicine Podcast 500th Ep Bonus AMA: Diabetes Meds, AI in Medicine, Thyroid Antibodies, Sleep Meds, Top 5 Lists, Favorite Failures, and More!
28 snips
Oct 8, 2025 In this special session, the hosts dive into stimulating topics like the promising role of AI in healthcare and the surprising links between antibiotic use and colorectal cancer risk. They also tackle insomnia treatments, discussing effective options beyond traditional medications. Thyroid health takes center stage with insights on the impact of selenium on antibodies. Personal reflections on career burnout and memorable failures round out the conversation, highlighting the importance of resilience and continual learning in medicine.
AI Snips
Chapters
Books
Transcript
Episode notes
Match Diabetes Therapy To Patient Capacity
- Prioritize treatments the patient can tolerate and is willing to use when selecting diabetes medications.
- Use insulin when it clearly best meets the patient's needs, but try to minimize long-term insulin burden when feasible.
Start With Lifestyle For New Diabetes
- Maximize lifestyle interventions early — diet changes and postprandial activity can dramatically lower glucose.
- Connect patients to resources and emphasize small sustainable steps rather than wholesale overhauls.
Fallback Oral Options When Novel Drugs Aren't Available
- If metformin and newer agents are unavailable, consider postprandial-focused options like meglitinides or morning-only gliclazide/glypizide.
- Recognize these agents manage glucose but lack organ-protective benefits seen with SGLT2/GLP-1 classes.
