SIO404: Are We Attracted To Our Mate's Immune System?
Nov 28, 2023
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The podcast explores the connection between attraction and immune system compatibility in relationships. It delves into the immune system's ability to handle challenges and advancements in vaccines. The chapters discuss genetics, the innate and adaptive immune system, and the impact of diversity on immune responses. The podcast also touches on transgender policies, COVID-19 immunity, and the role of genetic bottlenecks in evolution.
Attraction to partners with different immune systems may be influenced by the evolutionary benefits of diverse MHC molecules and stronger immune defenses.
Historical bottlenecks in human populations have shaped the diversity of the immune system, with certain immune system adaptations surviving due to genetic bottlenecks caused by specific pathogens like malaria.
Vaccines stimulate the immune response and enhance its ability to respond effectively to specific pathogens by triggering the production of specific antibodies and memory cells.
Deep dives
Hot dog buns and vampire dogs: Understanding the immune system's response to pathogens
The immune system has evolved unique strategies to combat different types of pathogens. When dealing with viruses, the immune system uses T cells to kill infected cells and antibodies to neutralize the virus. Bacteria, on the other hand, are targeted by neutrophils and other innate immune cells that release chemicals and DNA nets to trap and degrade the bacteria. The immune system's ability to recognize and respond to pathogens is facilitated by the diversity of MHC molecules, which act as hot dog buns presenting bacterial and viral proteins to T cells. The immune response is coordinated in lymph nodes, where T cells and B cells receive orders from each other and specific antibodies are produced to target the pathogen. This complex interaction is the result of millions of years of evolution and ensures the body's defense against harmful invaders.
Partner pairing and immune system diversity
Research has shown that individuals tend to be attracted to partners with different immune systems, as diversity in MHC molecules provides better protection against diverse pathogens. Studies have found that people are often more attracted to the body odor of individuals with different MHC alleles. This attraction may have evolutionary benefits, as individuals with diverse immune systems are more likely to produce offspring with stronger immune defenses. However, it's important to note that these findings apply to population-level trends and not individual compatibility.
Survival bottlenecks and the immune system
Historical bottlenecks in human populations, such as the 50,000 to 100,000-year-old bottleneck, may have played a role in shaping the diversity of the immune system. For example, theories suggest that the emergence of malaria may have caused a genetic bottleneck, resulting in the survival of individuals with certain immune system adaptations. This highlights the importance of diversity within the immune system in protecting the population against various pathogens.
Vaccine response and the immune system
Vaccines stimulate the immune response by triggering the production of specific antibodies and memory cells. This involves the coordination between T cells and B cells, with T cells giving orders to B cells to produce antibodies that can recognize and neutralize specific antigens. By vaccinating against specific pathogens, the immune system develops a memory of the pathogen, enhancing its ability to respond more effectively upon subsequent exposure. Vaccines have been instrumental in preventing the spread and severity of infectious diseases.
Conclusion
The immune system is a complex and highly evolved defense system that protects the body against pathogens. It involves intricate interactions between various cells, molecules, and processes. The immune response is tailored to different types of pathogens, such as viruses and bacteria, and relies on diversity within the immune system to provide effective defense. Studies have also shed light on the role of immune system diversity in partner attraction. Understanding the immune system's mechanisms and responses can help improve our knowledge of health and disease and aid in the development of effective treatments and preventive measures.
As crazy as that sounds, it seems to be the case! How does that work? And also... how does the immune system work? And can someone please explain it using vampires and hot dogs as analogies? If those are for some reason questions you've ever had, then Dr. Rick Sullivan is your guy! Are you an expert in something and want to be on the show? Apply here! Please please pretty please support the show on patreon! You get ad free episodes, early episodes, and other bonus content!
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