Sind Antikörper das ultimative "Heilmittel" in der Pandemie?

FAZ Wissen

Die Paper für diesen Podcast:

• Monoklonale Antikörper

Jakob Kreye et al, Cell, 2020, "A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology ina COVID-19 hamster model"

J. Kreyer et al, Nature Reviews Immunology, 2020, "Do cross-reactive antibodies cause neuropathology in COVID-19?"

Pressemitteilung von Regeneron: "Regeneron's REGN-COV2 Antibody Cocktail Reduced Viral Levels and Improved Symptoms in Non-Hospitalized COVID-19 Patients"

Review vom 31.7. A. Renn et al, Trends in Pharmacological Science, 2020, "Fruitful Neutralizing Antibody Pipeline Brings Hope To Defeat SARS-Cov-2"

• Nanobodies

Leo Hanke et al, Nature Communications, 2020, "An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction"

Michael Schoof et al, bioRxiv, 2020 "An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an 1inactive conformation"