

#151 Anaphylaxis with Dr Olajumoke Fadugba MD
19 snips May 27, 2019
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Recognizing Anaphylaxis Diagnosis
- Use the NIAID criteria to recognize anaphylaxis: acute symptoms with skin/mucosal involvement plus respiratory or cardiovascular compromise, or multiple organ systems.
- Identification requires history of exposure and symptoms like itching, vomiting, wheezing, or hypotension to guide timely diagnosis.
IgE vs Non-IgE Anaphylaxis
- IgE-mediated anaphylaxis involves prior sensitization and allergen-specific IgE triggering mast cell degranulation.
- Non-IgE mediated reactions, like to vancomycin, directly activate mast cells without IgE involvement and may be more preventable by premedication.
Epinephrine Use Counseling
- Counsel patients to use epinephrine if they feel a sense of impending doom, have symptoms in two organ systems, or show airway or blood pressure issues.
- Teach proper injection: mid-outer thigh through clothing, hold 10 seconds, and seek emergency care immediately after.