The Curbsiders Internal Medicine Podcast

#151 Anaphylaxis with Dr Olajumoke Fadugba MD

19 snips
May 27, 2019
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ADVICE

Recognizing Anaphylaxis Diagnosis

  • Use the NIAID criteria to recognize anaphylaxis: acute symptoms with skin/mucosal involvement plus respiratory or cardiovascular compromise, or multiple organ systems.
  • Identification requires history of exposure and symptoms like itching, vomiting, wheezing, or hypotension to guide timely diagnosis.
INSIGHT

IgE vs Non-IgE Anaphylaxis

  • IgE-mediated anaphylaxis involves prior sensitization and allergen-specific IgE triggering mast cell degranulation.
  • Non-IgE mediated reactions, like to vancomycin, directly activate mast cells without IgE involvement and may be more preventable by premedication.
ADVICE

Epinephrine Use Counseling

  • Counsel patients to use epinephrine if they feel a sense of impending doom, have symptoms in two organ systems, or show airway or blood pressure issues.
  • Teach proper injection: mid-outer thigh through clothing, hold 10 seconds, and seek emergency care immediately after.
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