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Cardiovascular-Kidney-Metabolic (CKM) Syndrome

28 snips
May 19, 2025
Dr. Ryan Bonner, nephrologist and medical educator at UNC, dives into the complexities of cardiovascular-kidney-metabolic (CKM) syndrome and its ties to chronic kidney disease. He unveils an innovative risk calculator that empowers healthcare providers to navigate these interconnected health issues. The discussion emphasizes effective obesity management, highlighting lifestyle changes and pharmacological options. Dr. Bonner advocates for a collaborative approach in treatment, underscoring the importance of multidisciplinary strategies and patient education for optimal outcomes.
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INSIGHT

Complex Nature of CKM Syndrome

  • CKM syndrome represents complex overlaps of chronic kidney disease, cardiovascular issues, and metabolic syndrome with common pathophysiology.
  • Patients with CKM face high risks of premature cardiac death and progression of their diseases.
ADVICE

Use PREVENT for Cardiovascular Risk

  • Use the AHA PREVENT calculator to estimate 10- and 30-year risk of ASCVD and heart failure in CKM patients.
  • Assess cumulative risk especially in younger patients to guide prevention aggressively.
ADVICE

Manage Obesity Multidisciplinary Way

  • Prioritize lifestyle modifications for obesity but consider GLP-1 receptor agonists when needed.
  • Collaborate with bariatric surgery teams as part of a multidisciplinary approach for kidney patients.
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