MIT Technology Review Narrated Is this the end of animal testing?
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Jan 29, 2025 Discover the groundbreaking potential of organ-on-a-chip technology as a humane alternative to animal testing. Learn about the recent advances that are reshaping medical research and fostering ethical drug development. Explore how this innovative approach not only enhances the accuracy of testing but also promotes health equity in clinical trials. The conversation highlights the intersection of scientific innovation and ethics, paving the way for a future without animal testing.
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Rotavirus Research Using Organ Chips
- Sean Moore, a pediatric gastroenterologist, studies rotavirus using organ chips.
- He aims to understand why vaccinated children in low-income countries have lower immunity compared to those in richer nations.
Organs-on-Chips as Alternatives to Animal Testing
- Animal studies are ineffective for identifying human treatments, with a 95% drug failure rate.
- Organs-on-chips offer a viable alternative, addressing ethical and practical limitations of human trials.
FDA Modernization Act and Non-Animal Testing
- Drug development requires demonstrating safety, efficacy, and manufacturability.
- The FDA Modernization Act now allows non-animal testing in preclinical trials, potentially leading to better and cheaper treatments.