Today, Explained The end of dieting
145 snips
Nov 11, 2025 
Sumita Mukhopadhyay, a writer and editor, shares her personal journey with the weight-loss drug Manjaro, detailing its emotional and physical effects. Dr. Dan Bessison, an endocrinologist, explains the evolving medical understanding of obesity and the revolutionary impact of GLP-1 drugs. They discuss how these medications change appetite and behavior, the historic stigma around weight loss treatments, and the challenges patients face when adjusting to life changes post-medication. Their insights reveal a new era in the conversation about dieting and health.
AI Snips
Chapters
Transcript
Episode notes
Fashion Editor's Weight Journey
- Sumita Mukhopadhyay described gaining weight while working at Teen Vogue and feeling conflicted about her changing body.
- She initially struggled to embrace plus-size identity amid industry attention and personal uncertainty.
Health Scare Prompted Medication
- Sumita detailed family stress, her father's diabetes death, and her own pre-diabetic labs prompting medical action.
- Her doctor recommended the weekly injectable Manjaro to slow digestion and reduce hunger.
Difficult Side Effects On Munjaro
- Sumita described intense nausea and chronic digestive side effects while on Manjaro that she had to manage long-term.
- She said side effects never fully disappeared but she learned to cope with them.