🧬 The Biotech Startups Podcast is powered by Excedr—helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science.

As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners.

"If you as a leader of a startup—no matter how small—or you as an employee of a big organization, you could be the agent of change."

In this episode of The Biotech Startups Podcast, Andrey Doronichev traces his path from launching mobile content in Russia to transforming YouTube for mobile, overcoming fierce Google-Apple rivalry to deliver the iOS app, and pioneering VR at Google. He candidly shares lessons in resilience, startup highs and lows, and the critical role of personal influence behind major milestones, culminating in his pivot to AI-powered biotech with OPTIC.

Listeners get practical insights into team-building, dealmaking psychology, and the dynamic realities of entrepreneurship in fast-changing industries.

Key topics covered:

The Power of Personal Agency: Individuals spark big change
Navigating Corporate Rivalry: Launching YouTube iOS amid fierce competition
Transitioning to VR at Google: Scrappy teams driving breakthrough ideas
Embracing Entrepreneurial Hardship: Surviving the startup ups and downs
Finding the Next Frontier: Pivoting from blockchain to AI biotech innovation

If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening.

Subscribe to the Podcast:

Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994

Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4

Youtube: https://www.youtube.com/@thebiotechstartupspodcast

Website: https://www.thebiotechstartupspodcast.com/

Find our guest, Andrey Doronichev, at these links:

LinkedIn: https://www.linkedin.com/in/doronichev/

Website: https://bioptic.io/

Find our host, Jon Chee, at these links:

LinkedIn: https://www.linkedin.com/in/jonchee

Learn more about Excedr:

LinkedIn: https://www.linkedin.com/company/excedr/

Website: https://www.excedr.com

Intro & Outro Songs Created by OkKyojin, Owned by Excedr:

Website: https://flow.page/kyojin

Resources & Articles:

Google Cardboard (VR and AR project): https://vr.google.com/cardboard/

Oculus VR (now Meta Quest): https://www.meta.com/quest/

Google Earth VR: https://www.meta.com/experiences/pcvr/google-earth-vr/1513995308673845/?srsltid=AfmBOoowOgA142QolPTP6W8-r4HUczHdvqIEoSi_s3VtWBDsWRXyO0tm

Google Expeditions: https://en.wikipedia.org/wiki/Google_Expeditions

Stadia (Google’s cloud gaming platform): https://stadia.google.com/

Companies, Universities, & People mentioned:

OPTIC: https://bioptic.io/

Google: https://www.google.com/

Apple: https://www.apple.com/

Kleiner Perkins: https://www.kleinerperkins.com/

Greylock: https://greylock.com/

Eric Schmidt: https://www.linkedin.com/in/eric-e-schmidt/

Timestamps:

00:00 Intro

01:43 The Power of Personal Experience and Early Insights

03:42 Hypergrowth at YouTube and the Mobile Internet Explosion

05:15 Leading YouTube Mobile: Challenges and Triumphs

07:11 The Google-Apple Rift and Negotiating the YouTube iOS App

08:39 Focusing On User Experience to Resolve Corporate Rivalry

10:44 Lessons in Change-Making and Deal Psychology

12:38 Post-YouTube: Entrepreneurial Yearning and VR Vision at Google

18:02 The Reality of Starting Over (Again and Again)

21:06 Entrepreneurial Mindset: Why You Should Join a Startup

22:37 Leaving Google: Seeking the Next Big Thing and Exploring AI

27:31 The OPTIC Journey: Blockchain Bet, Pivot, and Investor Lessons

31:36 Outro

The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.

The Patrick Madrid Show: September 25, 2025 - Hour 1