The Skeptics' Guide to the Universe

The Skeptics Guide #1049 - Aug 16 2025

24 snips
Aug 16, 2025
The hosts share thrilling tales from Alaska, including insights on grizzly and brown bears. A heartfelt tribute honors astronaut Jim Lovell and the Apollo 13 mission. The potential of lithium for Alzheimer's treatment sparks a deep discussion about funding and ethical challenges in research. Meanwhile, the buzz surrounding ChatGPT-5 reveals both its advancements and user concerns. The show also covers the intriguing realm of mini nuclear reactors and unverified celebrity health claims, blending humor with education throughout.
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ANECDOTE

Jim Lovell’s Calm Command

  • Jay Novella recounts Jim Lovell's NASA career and calm leadership during Apollo 13, emphasizing competence under pressure.
  • He highlights Lovell's persistence, missions (Gemini, Apollo 8 & 13), and the crew's lifesaving improvisation.
INSIGHT

Why Some People Don't Feel Music

  • Cara Santa Maria explains specific music anhedonia as intact hearing without reward linkage to music.
  • Researchers propose three causes: global reward dysfunction, auditory damage (amusia), or disconnect between auditory and reward circuits.
INSIGHT

Lithium Shows Promise In Alzheimer’s Models

  • Stephen Novella outlines evidence linking low brain lithium to increased amyloid and tau in Alzheimer's models.
  • Animal results using lithium orotate slowed or reversed memory loss, but translation to humans remains uncertain.
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