

The Skeptics Guide #1049 - Aug 16 2025
24 snips Aug 16, 2025
The hosts share thrilling tales from Alaska, including insights on grizzly and brown bears. A heartfelt tribute honors astronaut Jim Lovell and the Apollo 13 mission. The potential of lithium for Alzheimer's treatment sparks a deep discussion about funding and ethical challenges in research. Meanwhile, the buzz surrounding ChatGPT-5 reveals both its advancements and user concerns. The show also covers the intriguing realm of mini nuclear reactors and unverified celebrity health claims, blending humor with education throughout.
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Jim Lovell’s Calm Command
- Jay Novella recounts Jim Lovell's NASA career and calm leadership during Apollo 13, emphasizing competence under pressure.
- He highlights Lovell's persistence, missions (Gemini, Apollo 8 & 13), and the crew's lifesaving improvisation.
Why Some People Don't Feel Music
- Cara Santa Maria explains specific music anhedonia as intact hearing without reward linkage to music.
- Researchers propose three causes: global reward dysfunction, auditory damage (amusia), or disconnect between auditory and reward circuits.
Lithium Shows Promise In Alzheimer’s Models
- Stephen Novella outlines evidence linking low brain lithium to increased amyloid and tau in Alzheimer's models.
- Animal results using lithium orotate slowed or reversed memory loss, but translation to humans remains uncertain.