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The Brain Health Revolution Podcast

Laxatives "Cause" Dementia? A Discussion and Review of The Latest Research

Mar 16, 2023
In this podcast, the hosts discuss the relationship between laxative use and dementia risk, exploring the complexity of the topic. They delve into the different types of laxatives and their mechanisms of action. They also address factors affecting the gastrointestinal tract and the importance of addressing the underlying cause of constipation. Additionally, they provide insights on fiber intake, medication use, and how to improve bowel movements for optimal health.
44:15

Podcast summary created with Snipd AI

Quick takeaways

  • Regular laxative use is associated with an increased risk of dementia, especially with osmotic laxatives.
  • Constipation should be viewed as a potential early sign of neurodegenerative diseases and addressed through comprehensive assessment and consultation with healthcare professionals.

Deep dives

Use of Laxatives and Risk of Dementia

A recent study examined the association between chronic use of laxatives and the risk of developing dementia. The study followed over 500,000 individuals for an average of 10 years and found that regular laxative use was associated with a 51% increased risk of dementia. The risk of dementia further increased with the number of laxative types used, with those using two or more types having a 90% increased risk. Osmotic laxatives, such as lactulose and Miralax, were identified as the most harmful. The study highlighted the importance of addressing constipation and the underlying factors causing it, as constipation itself may be an early sign of neurodegenerative diseases. However, it is important to consider other confounding factors and speak to a healthcare professional for personalized advice.

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