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Renowned geneticist George Church talks about the evolution of genomic sequencing, DNA as data storage, AI in drug discovery, and his groundbreaking research on aging. He discusses the potential of protective gene therapies against viruses and emerging technologies in genome synthesis.
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Quick takeaways
- Evolution of genomic sequencing: short vs. long reads offer distinct advantages in accuracy and cost efficiency.
- Balancing privacy with blockchain: utilizing homomorphic encryption for secure genomic data sharing while maintaining privacy.
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Evolution of Sequencing: Short vs. Long Reads
The podcast delves into the evolving landscape of DNA sequencing, comparing the utility of short and long reads. Short reads excel in tagging and N-chip applications, while long reads, although slightly more expensive, offer low entry costs and enhanced accuracy at the individual base pair level, reducing common inaccuracies. The discussion highlights the potential for utilizing both short and long reads in applications like sequencing human genomes for genetic counseling, addressing specific needs such as accurately determining pathological repeats.
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Listen to the best highlights from the podcasts you love and dive into the full episode