Mastering Nutrition
B6 deficiency, and who is a man with high estrogen, what should they do? | Masterjohn Q&A Files #33
Dec 24, 2019
Masterjohn, a health expert, discusses the relationship between B6 deficiency and high estrogen levels in men. He highlights the importance of measuring quinolinate levels as a marker of B6 deficiency and suggests increasing B6 supplementation. He also emphasizes the need to optimize B6 levels, address iron and riboflavin issues, and manage estrogen to alleviate symptoms.
01:22:50
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Quick takeaways
- Excessive estrogen levels can lead to elevated tryptophan metabolites like quinolinate, a neurotoxin causing glutamate sensitivity.
- Supplementing with B6 up to 100mg, addressing potential deficiencies in iron and riboflavin, and lowering tryptophan intake can help manage estrogen-related issues.
Deep dives
Effects of Estrogen on Tryptophan and Niacin Conversion
Estrogen increases the conversion of tryptophan to niacin in the body. This is believed to support niacin status in women during pregnancy. However, excessive estrogen levels can lead to elevated tryptophan metabolites, such as quinilinate. Quinilinate is a neurotoxin that can cause neurotoxicity and glutamate sensitivity. To manage the effects of estrogen, reducing estrogen levels through lifestyle changes like avoiding alcohol, addressing environmental toxins, and managing weight may be helpful.
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