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Is the Peanut Allergy Dead?

18 snips
Oct 23, 2025
Dr. David Hill, an allergist at Children's Hospital of Philadelphia and leader of the Hill Lab, discusses groundbreaking research on peanut allergies. He reveals that early exposure, rather than avoidance, may prevent many food allergies in children. The conversation covers how peanut allergies typically develop, the implications of guideline changes in allergy management, and the ongoing resistance from some clinicians and parents. Hill emphasizes the importance of data-driven recommendations for public health and shares how he navigates uncertainty with families.
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ANECDOTE

A Young Professional Living With Peanut Allergy

  • Dr. Hill describes a patient in her 20s who still suffers severe peanut reactions as a young professional in Manhattan.
  • She experiences emergency-room worthy reactions one or two times a year despite living a normal life.
INSIGHT

How Early Avoidance Backfired

  • Early allergen avoidance likely contributed to rising food allergy rates over decades.
  • Introducing foods via the gut promotes immune tolerance and reduces allergy risk.
INSIGHT

LEAP Trial Changed Practice

  • The LEAP randomized trial provided strong evidence that early peanut introduction reduces allergy.
  • That trial triggered rapid guideline changes in 2015 and revisions in 2017.
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