
Crypto In America Coinbase’s John D'Agostino on Institutional Adoption, Market Liquidity, Bitcoin ETFs, & Regulation
Dec 10, 2025
John D'Agostino, Head of Institutional at Coinbase and a former commodities market expert, shares insights on the intersection of traditional finance and crypto. He discusses how liquidity needs drive institutional interest and the transformative impact of Bitcoin ETFs on market stability. John compares his experiences in oil markets to crypto, emphasizing the importance of diverse narratives for broad market participation. He also explores regulatory challenges, the potential of Coinbase's super app, and the ongoing trends in institutional product demand.
AI Snips
Chapters
Transcript
Episode notes
Liquidity Trumps Regulatory Clarity
- Liquidity, especially depth and breadth, is the top prerequisite for institutional crypto adoption.
- Regulatory clarity and alpha matter too, but without broad diverse liquidity institutions won’t scale positions quickly.
Houston Evacuation Revealed Market Fragility
- John recalls the NYMEX natural gas market drying up after a Houston evacuation to show lack of breadth.
- He uses that event to explain why many trades evaporated when participants were geographically concentrated.
ETFs Provide Stabilizing Commercial Demand
- ETFs act as surrogate commercial users and force rebalancing that stabilizes Bitcoin markets.
- That mandated demand brings new participant types and supports healthier market structure.

