My guest is Dr. Chris Palmer, M.D., a board-certified psychiatrist and professor at Harvard Medical School. He explains how specific nutrition, exercise, supplement-based, and other factors can improve mitochondrial health and thereby provide relief from adult and childhood ADHD, bipolar disorder, schizophrenia, and symptoms of autism. We discuss mitochondrial biology, whether vaccines can impact inflammation and mitochondrial health, and the potential ramifications. We also review creatine, methylene blue, and urolithin A, as well as the role of B vitamins and iron in treating depression. By the end of this episode, you will understand the powerful link between metabolic health and mental health, and the lifestyle, dietary, and other factors you can leverage to help overcome common mental health challenges and disorders.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

Our Place: https://fromourplace.com/huberman

LMNT: https://drinklmnt.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Function: https://functionhealth.com/huberman

Timestamps

00:00:00 Dr. Chris Palmer

00:02:15 Integrating Metabolic, Mental & Physical Health; Childhood Trauma & Risk

00:10:46 Sponsors: Our Place & LMNT

00:13:44 Depression Causes, Molecule Model?, Neuroplasticity?; Metabolism

00:22:20 Mitochondrial Functions, Stress Response, Mental Health

00:31:09 Sponsors: AG1 & Eight Sleep

00:33:59 Mitochondrial Health & 6 Pillars of Lifestyle Medicine

00:39:38 Stimulants, Mitochondria, Dopamine; Alcohol

00:45:47 Nicotine; Substance Use, Metabolic Health & Disease

00:52:23 Children, Energy & Metabolic Function; Diseases of Aging & Mental Disorders

00:59:18 Sponsor: Function

01:01:06 Diet & Metabolism; Ultra-Processed Foods, Additives, GRAS

01:09:30 Rebellious Spirit, Ultra-Processed Foods & Food Industry Funding

01:19:14 Ketogenic Diet, Epilepsy, Schizophrenia, Bipolar

01:22:52 Ketogenic Diet, Fasting & Mitochondria; Gut Microbiome, Brain Metabolism

01:30:06 Low-Fat Diets; Tool: Occasional Fasts; Ketogenic Diet; Intermittent Fasting

01:38:40 Nutrition Research, Food Industry Lobbyists; Ultra-Processed Foods, Addiction

01:46:55 Creatine & Mitochondrial Health

01:52:34 Methylene Blue & Mitochondria; Serotonin Syndrome

02:02:58 Urolithin A, Mitochondria Function; Supplements & Appropriate Use

02:11:14 Vitamin Deficiencies, Iron Deficiency

02:16:06 Vitamin B12 & Folate Deficiency, Autoimmune Disorders

02:24:48 Mental Illness & Root Causes

02:29:02 Vaccines, Inflammation, Mitochondria, Autism

02:39:17 Neurodevelopmental Disorder Onset & Follow-Up

02:45:31 Vaccines, Autism, Future Research; Mother Obesity & Diabetes

02:51:23 Father Obesity & Autism; Poor Metabolic Health, Blood Biomarkers

02:56:44 Assessing Metabolic Health & Biomarkers; National Institutes of Health (NIH)

03:02:59 Future Directions, Bridging Mental & Physical Health

03:09:27 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures

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The Stratosphere Lounge Episode 379