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Business Of Biotech
BoB@JPM: Tom Chalberg, Ph.D., Genascence
Feb 24, 2025
In a captivating discussion, Tom Chalberg, Founder and CEO of Genascence, shares his journey from academia to leading innovations in gene therapy. He dives into the evolution of gene treatment, focusing on addressing widespread conditions like osteoarthritis. The conversation reveals the complexities of navigating regulatory landscapes for common vs. rare diseases. Chalberg also discusses the exciting breakthroughs in gene therapy and the strategic partnerships critical for funding in today’s biotech climate, painting a vivid picture of the industry's future.
48:00
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Quick takeaways
- The evolution of gene therapy is shifting focus from rare diseases to common conditions like osteoarthritis, aiming to improve public health outcomes.
- Dr. Tom Chalberg's journey highlights the integration of academic research into the biotech industry, emphasizing the role of entrepreneurial spirit amidst financial challenges.
Deep dives
Transforming Gene Therapy for Common Conditions
A significant shift in gene therapy aims to make treatments accessible for common conditions like osteoarthritis, rather than being limited to rare diseases. The approach focuses on harnessing advancements in genetics to create effective therapies that can also address broader public health issues. By moving gene therapy from academic research into everyday healthcare, there’s potential to alleviate the burden faced by millions suffering from conditions currently managed only with pain control or temporary relief. This transformation is spearheaded by innovative thinkers like Dr. Tom Chalberg, who highlight the necessity of reorienting focus toward prevalent disorders.
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Discover
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Listen to the best highlights from the podcasts you love and dive into the full episode