In this episode of "PICU Doc on Call," Dr. Pradip Kamat and Dr. Rahul Damania dive into a fascinating case of a 9-month-old infant who comes in with hypoglycemia and seizures. Together, they break down the basics of glucose metabolism, walk through the causes of hypoglycemia, and discuss the best diagnostic strategies and acute management steps. They put a special spotlight on using diazoxide for hyperinsulinemic hypoglycemia, discussing not only how it works but also its potential side effects. The conversation also discusses dietary interventions for metabolic disorders and highlights the importance of rapid diagnosis and personalized treatment.

Show Highlights:

Pediatric hypoglycemia and its implications in infants
Case study of a 9-month-old infant with hypoglycemia and seizures
Physiology of glucose metabolism and its regulation
Causes of hypoglycemia, categorized into primary and secondary etiologies
Diagnostic approaches for identifying the cause of hypoglycemia
Initial management strategies for acute hypoglycemia
Long-term treatment options based on underlying causes
Importance of timely diagnosis and intervention in the PICU setting
Pharmacologic management of hyperinsulinemic hypoglycemia, including the use of diazoxide
Multidisciplinary care and follow-up for pediatric patients with hypoglycemia

References:

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