Ep. 141 What are the childhood brain signatures that predict chronic pain before it develops?

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Important insights from research are illuminating secrets of Chronic Pain in Children.

This episode looks at research into the complexities of chronic pain among children. Dr. Lenz discusses the growing understanding that chronic pain often arises from how the central nervous system interprets  sensory inputs. The episode highlights the importance of early detection and treatment of chronic pain in altering its lifelong course. Also, it emphasizes that neuroimaging studies have found specific correlations in the brain with chronic pain, but more research is needed. 

00:00 Introduction to Chronic Pain in Young People
01:00 Meet Your Host, Dr. Michael Lenz
01:44 The Struggles of Chronic Pain Patients
02:55 The Prevalence of Chronic Pain in Children
03:22 The Role of Pediatricians in Chronic Pain Management
03:51 Understanding Nociplastic Pain
05:10 The Importance of Early Identification and Treatment
05:56 The Adolescent Brain and Cognitive Development Study
09:58 The Role of Genetics in Chronic Pain
12:40 The Future of Chronic Pain Treatment
13:18 Understanding the Risk Factors for Chronic Pain
13:46 Is there a Role of Functional MRI in Chronic Pain Diagnosis
19:09 The Impact of Sex Differences on Chronic Pain
20:39 Conclusion: The Future of Chronic Pain Research
22:15 Final Thoughts 

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When I started this podcast—and the book that came before it—I had my patients in mind. Office visits are short, but understanding complex, often misunderstood conditions like fibromyalgia takes time. That’s why I created this space: to offer education, validation, and hope. If you’ve been told fibromyalgia “isn’t real” or that it’s “all in your head,” know this—I see you. I believe you. You’re not alone. This podcast aims to affirm your experience and explain the science behind it. Whether you live with fibromyalgia, care for someone who does, or are a healthcare professional looking to better support patients, you’ll find trusted, evidence-based insights here, drawn from my 28+ years as an MD.

Please remember to talk with your doctor about your symptoms and care. This content doesn’t replace personal medical advice.*