Key Point 1: The Evolution of CAR T-cell Therapy and Its Success in Treating Leukemias

CAR T-cell therapy has revolutionized the treatment of leukemias by engineering a patient's own immune cells to recognize and target cancer cells. The therapy has shown remarkable success in treating both adult and pediatric leukemias, with high complete response rates. The CAR T-cells, once infused into the patient, not only kill the cancer cells but also divide and replicate, creating a persistent and long-lasting immune response. The therapy has demonstrated long-term remissions, even in high-risk patients, making it an effective and promising approach for leukemia treatment.