High Intensity Health with Mike Mutzel, MS Dr. Peter Attia Appears to Change His View of LDL Cholesterol
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Mar 22, 2025 Dr. Peter Attia and lipidologist Tom Dayspring delve into cholesterol's pivotal role in atherosclerosis and cardiovascular health. They unpack overlooked risk factors like triglycerides and insulin resistance, emphasizing the importance of the triglycerides to HDL ratio. The conversation also highlights the nuances of LDL cholesterol, particularly in metabolically healthy individuals. Plus, they share intriguing insights on sauna therapy's benefits for heart health and explore the impact of Lipoprotein(a) on cardiovascular risk.
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Cholesterol's Role
- Dr. Attia emphasizes lowering LDL cholesterol to reduce cardiovascular disease risk.
- He acknowledges that cholesterol is necessary but insufficient to explain atherosclerosis fully.
Triglycerides and Insulin Resistance
- Lipidologist Tom Dayspring highlights triglycerides and insulin resistance as significant CVD risk factors.
- He prioritizes measuring triglycerides and ApoB as key biomarkers.
Lipoprotein Exchange
- High triglycerides, in insulin resistance, cause VLDLs and remnant lipoproteins to become cholesterol-enriched.
- This increases their circulation time and potential for atherosclerosis.