This month we are chatting with Dr. Sarah Milne from Murdoch Children’s Research Institute who is also the Coordinator of the Friedreich's Ataxia Clinic at Monash Health in Melbourne, Australia. Sarah is an expert in hereditary cerebellar ataxias and after completing her PhD in 2018 she is trying to bolster the evidence base about the right rehab for people with Friedreich’s Ataxia.
This episode will appeal to people treating Friedreich’s Ataxia or any of the inherited cerebellar ataxias, and to anyone who sees people with cerebellar pathology. Also of interest are the chats about challenges of rehabilitation research. The audio quality in this episode isn’t up to our usual standard with a lot of static happening – sorry!
2.01 Intro & career pathway
4.38 Friedreich’s ataxia
7.00 How is Friedreich’s ataxia different to the hereditary cerebellar ataxias?
8.36 Phenotypes in neurological conditions and the RCT paradigm
11.20 PhD results
15.02 State of the Friedreich’s ataxia evidence
16.49 Ataxia outcome measures
20.03 Ataxia assessment
24.25 Compensation vs optimal cerebellar functioning
27.00 What can imaging tell us about cerebellar conditions?
29.55 Treatment
36.16 Efficacy vs Effectiveness, challenges of rehab trials
39.23 Aquatic physio for this population
41.43 Episode reflection
Links
Research Gate
PhD - 4 studies – Pilot rehabilitation trial for people with Friedreich’s Ataxia. Clinical audit of LL spasticity relationship with ataxia severity & function. Sensitivity of balance, gait measures and instrumented measures of gait & balance change over time.
LinkedIn
University of Melbourne profile
Articles discussed:
Brain Changes Associated with Postural Training in Patients with Cerebellar Degeneration
Home aerobic training for cerebellar degenerative diseases: a randomized controlled trial
Cycling regimen induces spinal circuitry plasticity and improves leg muscle coordination in individuals with spinocerebellar ataxia
Pred
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