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https://bit.ly/DivalproexDepakoteNursingConsiderations Generic Name
Divalproex
Trade Name
Depakote
Indication
Seizures, manic episodes, prevention of headache
Action
Increases the level of GABA (inhibitory neurotransmitter) in CNS
Therapeutic Class
Anticonvulsant, vascular headache suppressants
Pharmacologic Class
None
Nursing Considerations
• May cause suicidal thoughts, agitation, dizziness, insomnia, hepatotoxicity, pancreatitis • Increases risk for bleeding with Warfarin • Use caution with MAOIs • Monitor liver function tests
