Ever since the first progestin was isolated and reproduced out of Mexican Yams in the early 1950s, the race was on to formulate a low-risk, highly effective, oral birth control agent. Birth control pills remain one of the most common medications used by reproductive age women. We are now in the 4th generation of synthetic progestins in the pill. But do these matter? Is anti-androgenic activity real or just something found in the lab? In this podcast, we will review not just the history of the pill but we will also review how to “choose the right one“. Thank you, Lindsey and Jeanna, for the recommendation.