Hold These Truths with Dan Crenshaw

A Psychedelic Breakthrough In the Treatment of Trauma and Addiction | Dr. Nolan Williams

Apr 26, 2024
Dr. Nolan Williams discusses a clinical trial using ibogaine to treat veterans with PTSD and addiction, achieving an 83% remission rate. They explore the unique effects of ibogaine compared to classic psychedelics, the potential for combating addiction, and the therapeutic journey individuals undergo with ibogaine treatment.
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INSIGHT

Real-World Trial Built From Veteran Demand

  • Nolan Williams built a trial around veterans who traveled to Mexico for ibogaine and performed deep neurobiology measures.
  • Many returned with resolution of PTSD, depression, anxiety, and even traumatic brain injury–an unprecedented result.
ANECDOTE

Veterans' Trips Sparked The Trial

  • The study arose because veterans traveled to Tijuana to self-administer ibogaine and reported strong benefits.
  • Williams' team then constructed the first neurobiology trial to systematically study those outcomes.
INSIGHT

Ibogaine Produces A Consistent Life Review

  • Ibogaine is an alkaloid from a West African shrub that at high doses induces a stereotyped life-review experience.
  • The drug consistently guides veterans through emotionally salient memories that support therapeutic recontextualization.
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