This Scientist Figured Out Why Your Appendix Isn't Useless
Feb 2, 2024
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Heather Smith, a Professor of Anatomy at Midwestern University and editor of The Anatomical Record, dives into the surprising functions of the appendix. Once deemed useless, she reveals its potential roles in gut health and immune function. After her own appendicitis at age 12, Heather became fascinated by this overlooked organ. She discusses revolutionary ideas for treating appendicitis that could reduce reliance on surgery, emphasizing the need for continued anatomical research to reshape our understanding of the human body.
The appendix serves important functions in supporting the immune system and preserving beneficial gut bacteria during gastrointestinal distress.
The diversity of appendices across mammalian species suggests its evolutionary adaptation and highlights the need to continually update our knowledge of the human body.
Deep dives
The Appendix: More Than Just a Useless Organ
Contrary to popular belief, the appendix serves important functions that can benefit our health. Research has shown that the appendix supports the immune system and helps fight off invading pathogens in the gut. It also acts as a safe house for beneficial gut bacteria during gastrointestinal distress, allowing the good bacteria to re-colonize the gut after a diarrheal episode. The distribution of appendices across mammalian evolution suggests that it has evolved multiple times, indicating its adaptive function. While the causes of appendicitis are still not fully understood, factors such as low fiber content in the diet leading to blockages in the appendix or an overreacting immune system due to excessive sanitization have been proposed. However, advancements in antibiotics and alternative treatments may offer potential alternatives to emergency surgery in the future.
Understanding the Appendix's Anatomy and Evolution
The human appendix is a small worm-like organ, approximately the size of a pinky finger, attached to the seagull, which is the first part of the large intestine. However, there are various types of appendices found in different species, ranging from vermiform in humans to elongated cecums in rabbits. Recent studies have mapped the distribution and evolution of the appendix across mammalian species, indicating that its appearance in different lineages suggests its functional relevance. The appendix's diverse anatomy and evolutionary history highlight the need to explore small anatomical details and regularly update our understanding of the human body.
The Potential for Future Approaches to Appendicitis
The emerging understanding of the appendix's functions raises questions about the future treatment of appendicitis. While current treatment involves emergency surgery to remove the inflamed appendix, promising alternatives are being explored. Antibiotics and other non-surgical treatments are being investigated as potential options for managing appendicitis without complete removal. Studies have also shown that individuals who have had their appendix removed may have a higher risk of certain infections. With accumulating evidence of the appendix's beneficial role, a future where appendicitis can be prevented or treated with less invasive methods seems plausible.
Back in the day, many of us heard that the appendix is a vestigial organ — at best, a body part that lost its purpose all those many years ago. At worst, an unnecessary clinger-on to the human body that, when ruptured, could be life threatening. But what if that narrative is wrong?
Heather Smith became obsessed with the appendix after hers was removed at age 12. After years of anatomy research, she's found that the appendix is not, in fact, useless. Reporter Selena Simmons-Duffin is in the host chair today to get the scoop on all things appendix.
Think it's time to give another part of the human body its due? Email us at shortwave@npr.org — we'd love to hear about it!