These Artificial Blood Platelets Could One Day Save Lives
May 14, 2024
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Discover the creation of synthetic blood platelets as a solution to platelet scarcity and their potential benefits in trauma treatment. Explore how these artificial platelets mimic natural behavior to avoid adverse reactions and abnormal clotting, offering exciting prospects for healthcare advancements.
Synthetic platelets address blood clotting demand by mimicking natural platelets' mechanics and shape.
Potential applications for synthetic platelets include emergency scenarios and aiding cancer patients with low platelet counts.
Deep dives
Synthetic Platelets Creation
Researchers have developed synthetic platelets to address the scarcity of natural platelets, crucial for blood clotting. These artificial substitutes, stored for longer periods, can be used in scenarios like traumatic injuries. The team utilized a hydrogel to create nanoparticles that mimic natural platelets' mechanics and shape, promoting clotting and healing by binding to fibrin. Synthetic platelets were effective in accelerating healing in animals with severe internal bleeding, requiring fewer doses compared to natural platelets.
Future Applications and Development
The synthetic platelets offer advantages like freeze-drying and storage flexibility, unlike natural platelets. Potential applications include emergency settings like ambulances or battlefields. Moreover, cancer patients with low platelet counts due to treatment could benefit. Companies like CellSimBioTech and Hyman Therapeutics are progressing synthetic platelets for clinical trials, anticipating human testing in the near future to determine their suitability for widespread use.