This Week in Virology TWiV 992: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses clearance of longstanding, immune-deficiency-associated, vaccine-derived poliovirus infection following remdesivir therapy for chronic SARS-CoV-2 infection, SARS-CoV-2 exposure in New York City rats, clinical characteristics and outcomes of children with SARS-CoV-2 infection during the Delta and Omicron variant-dominant periods in Korea, exhaled breath aerosol shedding of SARS-CoV-2 variants, outpatient treatment of COVID-19 and the development of long COVID over 10 months, Nirmatrelvir and the risk of post-acute sequelae of COVID-19, assessment of the risk of venous thromboembolism in nonhospitalized patients with COVID-19, and the optimal duration of systemic corticosteroids in COVID-19 treatment.
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Links for this episode- Clearance of vaccine-derived poliovirus following remdesivir therapy for SARS-CoV-2 infection (Frontiers)
- SARS-CoV-2 exposure in Norway rats from New York City (mBio)
- Clinical characteristics and outcomes of children with SARS-CoV-2 Infection in Korea (JKMS)
- Exhaled breath aerosol shedding of SARS-CoV-2 variants (CID)
- Outpatient treatment of COVID-19 and the development of Long COVID (The Lancet)
- Nirmatrelvir and the risk of post-acute sequelae of COVID-19 (medRxiv)
- Risk of venous thromboembolism in nonhospitalized patients with COVID-19 (JAMA)
- Optimal duration of systemic corticosteroids in COVID-19 treatment (OFID)
- Contribute to our ASTMH fundraiser at PWB
- Dr. Griffin’s treatment guide (pdf)
- Letters read on TWiV 992
- Don’t crush Paxlovid (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv