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The Drug Discovery World Podcast

Revolutionary technology for drug discovery and development

Jan 11, 2024
This podcast episode covers three written articles on the future of a cytomegalovirus vaccine, the role of predictive diagnostics in precision medicine, and making data work harder in the race to market. Topics include the challenges in developing CMV vaccines, the importance of diagnostics in personalized therapy, and leveraging data for faster drug development.
33:17

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Quick takeaways

  • mRNA technology shows potential in developing a vaccine for cytomegalovirus by priming the immune system to prevent infection.
  • Predictive diagnostics, including biomarkers and genetic testing, are crucial in ensuring the right patients receive the appropriate treatments.

Deep dives

mRNA technology may hold the future for a cytomegalovirus vaccine

The first article explores the development of a vaccine for cytomegalovirus (CMV) using mRNA technology. CMV is a widespread virus that can cause birth defects and severe neurological consequences. Previous attempts at developing vaccines for CMV have been unsuccessful. Moderna is currently conducting Phase III trials for an mRNA-based CMV vaccine, mRNA-1647, which targets key antigens in the virus. The vaccine shows potential in priming the immune system to prevent CMV infection and is being studied for its safety and efficacy.

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