Planetary Health First Mars Next, a Michael Mann production 164 Longevity Part 1: Special Summer Re-Release
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Aug 28, 2025 
Join notable guests Aubrey de Grey, longevity expert; Payal Bhandari, functional medicine physician; Paul Graywall, biotech entrepreneur; Lee Shapiro, health investment guru; and Thomas Clues, venture capitalist. They dive into the science of longevity, discussing innovative treatments and the role of AI in healthcare. Key topics include the importance of preventive care, investment opportunities in longevity, and the critical state of maternal health. They also explore how femtech can enhance women's health, all while advocating for narratives that empower patient advocacy.
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Longevity Targets Aging, Not Immortality
- Aubrey de Grey frames longevity as making people live healthier for longer by targeting aging itself.
- He argues we're within reach of lab proof-of-concept for medicines that extend healthy, youthful life.
Healthspan Is Central To Longevity
- Payal Bhandari links longevity to expanding lifespan and increasing healthspan by improving cellular function and the microbiome.
- She warns chronic, preventable conditions are appearing younger and driving healthcare burdens.
Longer Lives Reveal Age-Related Disease
- Aubrey adds that age-related diseases rise because more people survive early mortality, making late-life illness the main problem.
- He treats longevity as both lifespan and healthspan extension, with health improvements driving longer lives.