Open Letter To The NIH

Sep 2, 2025

In an urgent call for action, scientists and healthcare professionals push for the NIH to allocate $5 billion for crucial medical research. They stress the importance of spending appropriated funds effectively before the fiscal year ends. The discussion reveals concerns about potential retaliation against critics and the need for a unified voice in demanding accountability. This collective effort aims to promote biomedical advancements and ensure that vital research funding isn't lost.

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INSIGHT

Retaliation Drives Anonymous Crowdsourcing

The podcast explains that the Trump administration has been retaliating against critics and others are channeling criticism through intermediaries.
This context motivates an open letter seeking signatures from medical professionals to avoid singling out originators.

ADVICE

Who Should Sign And How To Help

Signatories should be scientists, doctors, or healthcare professionals and sign the open letter via the provided link.
Email nihfundingletter@gmail.com to help organize or promote the letter more broadly.

INSIGHT

Unspent NIH Funds Risk Lost Research

The core issue is that NIH has reportedly spent at least $5 billion less than Congress appropriated, risking lost research opportunities.
The fiscal year deadline (September 30) makes timely obligating funds urgent because unspent money will vanish.

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You can sign the letter here.

The Trump administration has been retaliating against its critics, and people and groups with business before the administration have started laundering criticism through other sources with less need for goodwill. So I have been asked to share an open letter, which needs signatures from scientists, doctors, and healthcare professionals. The authors tell me (THIS IS NOT THE CONTENTS OF THE LETTER, IT’S THEIR EXPLANATION, TO ME, OF WHAT THE LETTER IS FOR):

The NIH has spent at least $5 billion less of that money than Congress has appropriated to them, which is bad because medical research is good and we want more of it.

In May, NIH Director Jay Bhattacharya told a room full of people that he would spend all the money by the end of the fiscal year. That is good news, because any money not spent by that point will disappear. The bad news is the fiscal year ends on September 30th and according to the American Association of Medical Colleges, “the true shortfall far exceeds $5 billion.”

Our open letter requests that Dr. Bhattacharya do what he said he would and spend all the money by September 30th.

We as the originators of the letter do not want to be named publicly because we are concerned about being the focal point for blame and retaliation. We would rather be members of a large crowd of signatories than be singled out as individuals to make an example of. Based on our understanding of current administration norms, we do not expect retaliation against private individuals who sign this letter.

We are looking for signatures from scientists, doctors, and healthcare professionals. So if that is you, please sign here. If you want to help support the letter more broadly, email nihfundingletter@gmail.com. Our stretch goal is to have a thousand people sign the letter within the next two weeks.

To hammer home (since many people failed to understand it) that this is not the contents of the letter, I am including the actual contents below:

We, the undersigned scientists, doctors, and public health stakeholders, commend your commitment to spend all funds allocated to the NIH, as reported in The Washington Post. At the same time, we are concerned by reports that U.S. institutions received nearly $5 billion less in NIH awards over the past year. With less than one month to the end of the fiscal year, we submit this urgent request to ensure that your commitment is upheld. If you anticipate that all appropriated funds cannot be spent in time, we request a public disclosure of the barriers preventing the achievement of this crucial responsibility.

We present this request in the spirit of the broad, bipartisan consensus in favor of spending appropriated NIH funds. In their July letter to the Office of Management and Budget, fourteen Republican senators, led by Senators Collins, Britt, and McConnell, forcefully argued that suspension of NIH funds “could threaten Americans' ability to access better treatments and limit our nation's leadership in biomedical science.” The case for investment in medical research transcends political divides as it serves our collective national interest.

The return on investment from research is compelling. Synthesizing the empirical literature, economist Matt Clancy estimates that each public and private R&D dollar yields roughly $5.50 in GDP—and about $11 when broader benefits are counted. Every dollar of NIH funding not deployed represents lost opportunities for breakthrough treatments, missed chances to train the next generation of scientists, and diminished returns on America's innovation ecosystem.

Spending these funds is also a competitiveness imperative as China attempts to transform itself from a low-end manufacturer to a high-tech research and innovation juggernaut. In 2024, the Chinese government increased its spending on science and technology by 10%, and the nation’s total expenditure on research and development increased by 50% in nominal terms between 2020 and 2024. As China’s number of clinical trials and new drug candidates begin to outpace the U.S., America cannot afford to allow biomedical research funding to go unspent.

We respectfully ask that you ensure that NIH will obligate all FY25 funds by September 30, 2025, and, if that is not possible, that you address the scientific community to explain why and what must be done to ensure all appropriated funds are spent in FY26. We stand ready to support your efforts to preserve this vital national investment.

https://readscottalexander.com/posts/acx-open-letter-to-the-nih