The Beyond Tomorrow Podcast with Julian Issa AI CAN’T SOLVE AGING… Unless You Do THIS First - Carina Kern
What if aging is not an inevitable decline but a solvable systems problem hiding in plain sight?
Julian sits down with Carina Kern, a scientist working at the intersection of longevity research and medicine, for a wide ranging conversation on how aging actually works inside the body. Together, they explore why traditional medicine has struggled to address age-related decline and why treating one disease or one organ at a time may be missing the bigger picture. Carina introduces a systems level way of thinking about aging, explaining how cellular damage spreads across the body and why identifying key biological nodes could change how we prevent degeneration altogether.
Julian and Carina also dive into Carina’s research on necrosis, a form of uncontrolled cell death that may sit at the core of aging and many chronic diseases. Carina explains how her team is developing a first in class anti necrotic therapy, how artificial intelligence is being used to uncover system wide interventions, and why the kidney has become a powerful model for studying accelerated aging. The conversation expands beyond Earth as well, touching on what space travel reveals about rapid aging and why protecting human biology may be essential for the future of human exploration.
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What You’ll Learn
Why aging is a multifactorial systems problem rather than a single disease
How traditional medicine struggles to treat age related degeneration
What necrosis is and why it may drive aging and chronic illness
How blocking cell death could protect multiple organs at once
The role of AI in discovering longevity therapies
Why longevity research needs scientific rigor over hype
⏱ Timestamps
00:00 Intro
00:27 Linking Longevity and Medicine
02:44 Witnessing a Loved One’s Health Decline
05:17 Introducing the Blueprint Theory
09:03 The Hidden Risks of Unintended Consequences
11:52 Which Hallmarks of Aging Matter Most
18:59 Why Clinical Trials Still Matter
20:48 If You Believe It Works, Prove It
21:47 Inside Anti Necrosis Therapy
26:54 Why the Kidney Matters in Longevity
28:33 Targeting the Root of Degeneration
29:29 Why Necrosis Drives Degenerative Disease
31:06 Building the Right Team Around You
33:27 Can Artificial Intelligence Solve Aging
38:11 Do Astronauts Age Faster in Space
39:29 Why Longevity Is About Interventions
41:16 Preventing Debilitating Health Decline
42:33 Rethinking How We Treat Disease
45:23 How Scalable Is Anti Necrosis Therapy
47:29 Why Longevity Is More Than Wellness
50:38 When Does Necrosis Really Begin
52:03 Is Aging an Engineering Challenge
54:01 Focusing on the End Goal That Matters
55:36 A Vision for the World in 2030
56:17 Where the Longevity Space Is Headed
Connect with Julian
📸 Instagram: @thebeyondtomorrowpodcast
🌐 Website: www.beyondtomorrowpodcast.com
📩 Email: bookings@beyondtomorrowpodcast.com
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Follow Carina:
Instagram: https://www.instagram.com/dr_carinakern
LinkedIn: https://uk.linkedin.com/in/carina-carla-kern
YouTube: https://www.youtube.com/@DrCarinaCarlaKern
X: https://x.com/CarinaCarlaKern
LinkGevity: https://www.linkgevity.com/